Picarro air quality analysis systems have established themselves as the “gold standard” in measurement technology at atmospheric stations around the world (e.g. WMO, GAW). The innovative and disruptive nature of this technology has led to a measurement revolution in other applications as well. At present, Picarro analyzers are deployed to monitor vehicle emissions (H2S), fenceline emissions near industrial facilities (HF, H2S, C2H4O), air quality inside sterilized spaces (H2O2, C2H4O), they are used to quantify community exposure to toxic gases (H2CO, HF, C2H4O), to quantify the emissions of greenhouse gases from urban, industrial and rural infrastructure (CO2, CH4, CO and NH3), and many others. The portable form factor of the analyzer has allowed measurement campaigns to transfer bench-top performance to mobile deployments, be that on land, water or air.